New Horizons Session
NH 16 - The brain's waste facility: the glymphatic system
Lectures
1
Chairperson's introduction
05:00Tchoyoson Lim, Singapore / SG
2
Current concepts in intracranial interstitial fluid transport and the glymphatic system
20:00Shinji Naganawa, Nagoya / JP
3
Imaging techniques for the glymphatic system
20:00Geir Andrè Ringstad, Oslo / NO
4
Glymphatic waste clearance and neurological diseases
20:00Toshiaki Taoka, Nagoya / JP
5
Panel discussion: Cerebrospinal, interstitial fluids and glymphatic system
25:00Panel discussion: Cerebrospinal, interstitial fluids and glymphatic system
5 min
Chairperson's introduction
Tchoyoson Lim, Singapore / Singapore
20 min
Current concepts in intracranial interstitial fluid transport and the glymphatic system
Shinji Naganawa, Nagoya / Japan
1. To name and identify the two major concepts of the waste clearance system of the brain.
2. To list three of the causes for the impaired function of the glymphatic system.
3. To describe and reflect on how impaired function of the glymphatic system relates to neurodegenerative diseases.
2. To list three of the causes for the impaired function of the glymphatic system.
3. To describe and reflect on how impaired function of the glymphatic system relates to neurodegenerative diseases.
20 min
Imaging techniques for the glymphatic system
Geir Andrè Ringstad, Oslo / Norway
1. To name and identify advantages and disadvantages of intrathecal vs intravenous contrast-enhanced MRI for imaging the glymphatic system.
2. To describe how MRI can be employed to study driving forces of the glymphatic system.
3. To describe how ultra-high field MRI can be used to measure CSF-mobility in perivascular spaces.
2. To describe how MRI can be employed to study driving forces of the glymphatic system.
3. To describe how ultra-high field MRI can be used to measure CSF-mobility in perivascular spaces.
20 min
Glymphatic waste clearance and neurological diseases
Toshiaki Taoka, Nagoya / Japan
1. To summarise the dynamics of the cerebrospinal fluid (CSF) and interstitial fluid (ISF) dynamics.
2. To understand the mechanism in the various pathological conditions in which the CSF/ISF dynamics are impaired.
3. To describe the imaging technique to evaluate the CSF/ISF dynamics.
2. To understand the mechanism in the various pathological conditions in which the CSF/ISF dynamics are impaired.
3. To describe the imaging technique to evaluate the CSF/ISF dynamics.
25 min
Panel discussion: Cerebrospinal, interstitial fluids and glymphatic system