Personalized Weight-Tiered Protocols in Angiotomography: The Synergy Between Canon Prime SP and Stellant SmartFlow Injector in Improving Diagnostic Quality
Author Block: J. T. d. S. d. Castro, D. C. Novais da Silva, H. d. J. Ferreira, D. Yamada, S. San Juan Dertkigil, F. Reis; Campinas/BR
Purpose: Diagnostic quality in angiotomography relies on adequate vascular opacification (arterial Hounsfield Units, HU). Even with advanced technologies, standardized protocols ignoring patient weight often lead to suboptimal contrast. A study at HC-UNICAMP with 1,082 CTAs confirmed significant influence of weight, venous access type/caliber, contrast flow on arterial density. These findings informed personalized, weight-tiered protocols starting June 1, 2025.
Methods or Background: Retrospective analysis included 1,082 CTA exams performed with a Canon Prime SP 80-channel CT, Stellant SmartFlow injector (Bayer), and 300 mg/mL iodinated contrast. Variables collected included weight, age, venous access type/caliber, contrast flow, and arterial HU. Exams were quality-classified per ACR criteria: <250 HU (poor), 251–349 HU (average), and ≥350 HU (excellent). Following this analysis, new personalized weight-tiered protocols were implemented from June 2025, adjusting kVp, flow, contrast volume, and dose modulation for specific weight ranges (e.g., PE protocol for weights up to >100kg), with tailored parameters for each.
Results or Findings: Preliminary data shows significant improvement in contrast opacification: the percentage of exams >350 HU increased from 30% to 70%. An approximate 15% reduction in effective radiation dose was also observed. These are partial results from over 140 exams performed up to June 25, 2025, indicating that the personalized angiotomography protocols are extremely promising.
Conclusion: The implementation of personalized weight-tiered protocols in angiotomography at HC-UNICAMP marks a data-driven shift, optimizing diagnostic quality while reducing radiation dose and contrast volume. The synergy between the Canon Prime SP CT and Stellant SmartFlow injector, coupled with the radiology team's input, was crucial. This project serves as a model for other institutions, with prospective monitoring and full results to be presented at ESR2026.
Limitations: Results are being updated according to the new protocol's implementation, with ongoing data collection.
Funding for this study: Not applicable.
Has your study been approved by an ethics committee? Yes
Ethics committee - additional information: The submission to the Ethics Committee/IRB is currently under review