Unique aortic remodeling and device-related complications after PETTICOAT endovascular repair
Author Block: N. Kerschbaumer1, A. Fereydooni1, D. Vigneault1, K. Bäumler1, G. Mistelbauer1, D. Mastrodicasa2, E. George1, D. Fleischmann1; 1Stanford, CA/US, 2Seattle, WA/US
Purpose: To identify anatomic and device-related factors associated with aortic remodeling and complications following PETTICOAT(Provisional-Extension-To-Induce-Complete-Attachment).
Methods or Background: The concept of scaffolding the aortic true lumen (TL) with bare-stent distal to standard TEVAR has become valuable in dissection treatment. However, anatomical and technical factors associated with treatment outcomes have not been established.
In this observational, single-center study two cardiovascular radiologists reviewed a retrospective cohort of 64 patients with complicated type-B-dissection or residual descending dissection after type-A-repair, treated with distal bare-stent extension. Available pre-/postoperative and follow-up (median 15 months) CT-angiograms were assessed.
Results or Findings: We identified four distinct, PETTICOAT-specific phenomena:
First, small contrast jets into the false lumen (FL) through dissection flap fenestrations corresponding to intercostal arteries were observed at several bare-stent levels, typically thrombosing throughout follow-up.
Second, in contrast to covered endografts, the aortic TL can fully re-expand, even beyond the diameter of the bare-stent, with gradual complete absorption of the FL thrombus (n=1).
Third, we observed new focal contrast outpouchings in the dissection flap separating the TL from the thrombosed FL (proposed term: ‘junctional SINE’) at the junction between covered and uncovered stents (n=2). These can be explained as intimal erosions caused by protruding bare-stent wires, associated with abrupt caliber changes and ‘telescoping’ where the bare-stent exits the endograft.
Fourth, all cases of bare-stent migration (n=3), were associated with junctional SINEs. Predisposing factors for migration were short device overlaps within angulated aortic segments.
Conclusion: Temporary intercostal fenestrations and TL re-expansion beyond device diameter may be part of normal healing. The prognosis of ‘junctional SINEs’ and their association with aortic angulation and device migration may impact patient selection and device design.
Limitations: This study identified unique imaging features, but is underpowered to establish prognostic significance of these observations.
Funding for this study: None
Has your study been approved by an ethics committee? Yes
Ethics committee - additional information: IRB Stanford University, eProtocol #52791