Gadopiclenol (Vueway) is a new, highly stable gadolinium-based contrast agent (GBCA) for MRI whose r1 relaxivity is 2-3 times higher than the r1 relaxivity values of other currently available GBCAs. It is approved in the USA and Europe for CNS and body indications at a dose of 0.05 mmol/kg bodyweight which is half that of other purely extracellular fluid GBCAs. This means that patients are exposed to half the amount of gadolinium without loss of diagnostic information, and that half the amount of gadolinium enters the environment. This symposium will focus on the safety of gadopiclenol, on its role in improving environmental sustainability and on the clinical benefits of 0.05 mmol/kg gadopiclenol specifically in MRI of the CNS and abdomen.
Introduction
Francesco Sardanelli, Milan / Italy
Safety and sustainability: evaluating the impact of reduced dose gadopiclenol
Alberto Spinazzi, Monroe Township / United States
To provide up-to-date information on the clinical safety of gadopiclenol ; To describe how a reduced dose of gadolinium is a more sustainable solution for contrast-enhanced MRI
Gadopiclenol: the advantages of high relaxivity for MR imaging of the CNS
Simonetta Gerevini, Cremona / Italy
To demonstrate how higher r1 relaxivity permits GBCA dose lowering for CNS applications without loss of diagnostic information
Oncologic imaging: a case view of gadopiclenol across approved indications
Guenther Schneider, Homburg/Saar / Germany
To demonstrate the benefits of 0.05 mmol/kg gadopiclenol for MRI of abdominal organs
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